Alopecia areata Lidia Rudnicka Department of Dermatology, Medical - - PowerPoint PPT Presentation

alopecia areata
SMART_READER_LITE
LIVE PREVIEW

Alopecia areata Lidia Rudnicka Department of Dermatology, Medical - - PowerPoint PPT Presentation

Alopecia areata Lidia Rudnicka Department of Dermatology, Medical University of Warsaw Poland lidiarudnicka@gmail.com I have no relevant conflicts of interest anagen phase Hair cycle telogen phase catagen phase anagen effluvium Anagen


slide-1
SLIDE 1

Alopecia areata

Lidia Rudnicka

Department of Dermatology, Medical University of Warsaw Poland

I have no relevant conflicts of interest lidiarudnicka@gmail.com

slide-2
SLIDE 2

Hair cycle

anagen phase catagen phase telogen phase

slide-3
SLIDE 3

Anagen effluvium occurs after any insult to the hair follicle that impairs its mitotic activity. anagen effluvium Causes: Inflammatory (alopecia areata) Drug-induced (chemotherapy, retinoids) Toxic (thallium, arsenic) Extreme nutrient deficiencies

slide-4
SLIDE 4

High mitotic activity - thick hair Low mitotic activity - thin hair No mitotic activity - no hair

slide-5
SLIDE 5
  • Rare trichoscopy features of AA
  • Trichoscopic cases in AA
  • Common trichoscopy features of AA
slide-6
SLIDE 6

Exclamation mark hairs Black dots Yellow dots

Alopecia areata in trichoscopy

slide-7
SLIDE 7

Multiple exclamation mark hairs = high disease activity

slide-8
SLIDE 8

Inui et al. 2009

Alopecia areata – tapered hairs

Tapered hairs are elongated exclamation mark hairs

slide-9
SLIDE 9

Pohl-Pinkus constrictions and monilethrix-like hairs in alopecia areata

These hairs differ from true monilethrix by the irregular distribution

  • f constrictions
slide-10
SLIDE 10

Alopecia areata – black dots

slide-11
SLIDE 11

black dots a marker of high disease activity in alopecia areata but not specific for alopecia areata

slide-12
SLIDE 12

Alopecia areata – yellow dots

slide-13
SLIDE 13
  • S. Inui . Trichoscopy in Asian Skin in Atlas of Trichoscopy, 2012

Yellow dots may not be visible in Asian patients

slide-14
SLIDE 14
slide-15
SLIDE 15
  • Rare trichoscopy features of AA
  • Trichoscopic cases in AA
  • Common trichoscopy features of AA
slide-16
SLIDE 16

Alopecia areata – vellus hairs

Caucasian Asian

Marker of disease severity ?

Inui et al

slide-17
SLIDE 17
  • Trichorrhexis nodosa
  • Zigzag hairs
slide-18
SLIDE 18

Zigzag hairs

slide-19
SLIDE 19

Alopecia areata – regrowing hairs

circle pigtail

70x

slide-20
SLIDE 20
slide-21
SLIDE 21

Trichoscopy feature % of patients with AA

Yellow dots 63-94% Black dots 44-70% Exclamation mark hairs 30-44% Tapered hairs 12-42% Broken hairs 45-58% Vellus hairs 33-72% Trichorrhexis nodosa 3-16% Monilethrix-like hairs 2-3% Pohl-Pinkus constrictions Regrowing hairs

Source: Atlas of Trichoscopy, 2012

slide-22
SLIDE 22
  • Rare trichoscopy features of AA
  • Trichoscopic cases in AA
  • Common trichoscopy features of AA
slide-23
SLIDE 23
slide-24
SLIDE 24

43 – year old woman Chemotherapy – induced alopecia

slide-25
SLIDE 25
slide-26
SLIDE 26