Congo N Engl J Med 2014;371:1375 N Engl J Med 2014;371:1418 As of - - PowerPoint PPT Presentation

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Congo N Engl J Med 2014;371:1375 N Engl J Med 2014;371:1418 As of - - PowerPoint PPT Presentation

Aug 11, 2023 30 likes •241 views

Zaire Ebola Virus (x40,000) Congo N Engl J Med 2014;371:1375 N Engl J Med 2014;371:1418 As of November 11, 2014 Secondary Transmission 1976 Zaire 5.6% among all family contacts maximum, 15% Highest risk with delivery of child

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Zaire Ebola Virus (x40,000)

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Congo

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N Engl J Med 2014;371:1375

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N Engl J Med 2014;371:1418

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As of November 11, 2014

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Secondary Transmission

1976 Zaire

  • 5.6% among all family contacts – maximum, 15%
  • Highest risk with delivery of child

1985 Congo

  • 16% household contacts
  • No cases without physical contact

1996 South Africa

  • healthcare workers exposed to an infected, undiagnosed

physician: one secondary case due to blood contact – more than 300 providers using standard precautions exposed

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Ebola Virus Disease

  • Usually abrupt onset 5 –10 days after “exposure.”
  • Initial symptoms: fever, headache, malaise, anorexia,

myalgia, arthralgia, sore throat, retrosternal pain, conjunctival injection, lumbosacral pain, rash.

  • Gastrointestinal symptoms follow in first few days:

nausea, abdominal pain, vomiting (67%), diarrhea (66%).

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EPIDEMIOLOGY OF EBOLA VIRUS DISEASE

Anthony L. Esposito, MD Chief, Department of Medicine Hospital Epidemiologist Saint Vincent Hospital Professor of Medicine University of Massachusetts School of Medicine

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Thank You

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Ebola River, 1976