Initial Results from Multiple Irradiations of an Anthropomorphic - - PowerPoint PPT Presentation

initial results from multiple irradiations of an
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Initial Results from Multiple Irradiations of an Anthropomorphic - - PowerPoint PPT Presentation

Initial Results from Multiple Irradiations of an Anthropomorphic Spine Phantom Andrea Molineu, Nadia Hernandez, Paola Alvarez, David Followill, Geoffrey Ibbott Spine phantom heart esophagus lung lung PTV spinal bone cord Treatment Plan


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SLIDE 1

Initial Results from Multiple Irradiations

  • f an Anthropomorphic Spine Phantom

Andrea Molineu, Nadia Hernandez, Paola Alvarez, David Followill, Geoffrey Ibbott

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SLIDE 2

lung lung heart

Spine phantom

PTV bone spinal cord esophagus

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SLIDE 3

Treatment Plan

  • 6 Gy to at least 90% of PTV
  • Min PTV dose at least 5.25 Gy

2.78 1000 cc Whole Lung 9.75 8.63 <10 cc Skin 6.00 4.46 <5 cc Esophagus 8.25 6.00 <15 cc Heart 5.25 3.75 2.63 <0.35 cc <1.2 cc Spinal Cord Max Point Dose (Gy) Volume Max (Gy) Volume Normal structure

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SLIDE 4

Representative Treatment Plan

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SLIDE 5

Criteria

  • TLD

±7%

  • Film (axial and sagittal

planes) 85% meet 5%/3mm

  • Plan DVH

must comply with protocol

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SLIDE 6

Good Agreement

Plan Measurement

PTV Cord/bone OAR

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SLIDE 7

Good Agreement

Gamma Measurement 100% passing

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SLIDE 8

Poor Agreement

PTV Cord/bone OAR

Measurement Plan

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SLIDE 9

Poor Agreement

Gamma Measurement 100% passing 26% passing

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SLIDE 10

Overall results

  • 41 irradiations at 35 institutions
  • 17 irradiations failed
  • 1 failed TLD criteria only
  • 8 failed gamma criteria only
  • 8 failed both TLD and gamma
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SLIDE 11

All Results

42 - 99 22 - 100 0.67 - 1.51 0.88 - 1.15 range 14.6 16.4 0.17 0.05 std dev 86 85 1.02 0.99 mean Sagittal Gamma Axial Gamma Heart PTV

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SLIDE 12

Passing Results

85 - 99 85 - 100 0.67 - 1.18 0.93 - 1.03 range 5.1 4.6 0.12 0.03 std dev 94 94 1.02 0.99 mean Sagittal Gamma Axial Gamma Heart PTV

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SLIDE 13

Results by Machine

8 8 1 24 41 total 2 3 8 13 Varian 1 1 2 TomoTherapy 1 1 2 Siemens 2 1 10 13 Novalis 2 2 2 6 Elekta 2 1 2 5 CyberKnife

Dose and Gamma Gamma TLD Dose Criteria Failed Passes Irradiations

Machine Manufacturer

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SLIDE 14

Results by TPS

8 8 1 24 41

total

1 1 1 3

superposition XiO

1 1 3 5

convolution

Pinnacle

1 7 8

pencil beam

1 1 2 4

Monte Carlo iPlan

1 1 2

superposition Hi-Art

1 1 2

pencil beam

1 4 7 12

AAA Eclipse

2 1 1 4

raytracing

1 1

Monte Carlo CyberKnife Dose and Gamma Gamma TLD Dose Criteria Failed Passes Irradiations

Algorithm TPS

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SLIDE 15

Results by Algorithm

8 8 1 24 41

total

2 1 1 4

raytracing

2 8 10

pencil beam

1 1 3 5

Monte Carlo

2 3 5 10

superposition/ convolution

1 4 7 12

AAA Dose and Gamma Gamma Dose Criteria Failed Passes Irradiations Algorithm

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SLIDE 16

Conclusions

  • Challenging credentialing

process

  • Treatment couch should be

considered in these treatments

  • Cannot make generalizations

with regard to machine, TPS,

  • r algorithm
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SLIDE 17

Thank you.

The investigation was supported by PHS grants CA10953 and CA81647 awarded by the NCI, DHHS.