injections; experience in a DGH Dr Sara Farrell (ST3) Dr Jennifer - - PowerPoint PPT Presentation

injections experience in a dgh
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injections; experience in a DGH Dr Sara Farrell (ST3) Dr Jennifer - - PowerPoint PPT Presentation

Outpatient Bulkamid injections; experience in a DGH Dr Sara Farrell (ST3) Dr Jennifer Davies (Consultant O&G) your hospitals, your health, our priority ST05_Mar12 Conflict of interest; JD has received payment from Speciality


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your hospitals, your health, our priority

ST05_Mar12

Outpatient Bulkamid injections; experience in a DGH

Dr Sara Farrell (ST3) Dr Jennifer Davies (Consultant O&G)

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your hospitals, your health, our priority

ST05_Mar12

  • Conflict of interest;

JD has received payment from Speciality European Pharma for speaking at Bulkamid master classes.

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Bulkamid at WWL

  • Offered as a treatment option to all
  • Performed as an out patient
  • Pre-treatment analgesia
  • Local anaesthetic
  • 2 ml in 3 deposits
  • Prophylactic antibiotics for UTI - 3 days
  • Home after satisfactory void
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Patient group

  • 55 women (60 procedures) with USI +/-
  • veractive bladder
  • From June 2012 to July 2014
  • Bulkamid injections carried out in the
  • utpatient clinic (hysteroscopy room)
  • Follow up

–8 -12 weeks – 12 months (24 patients eligible)

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Age

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Reason for using Bulkamid

  • Patient choice

23

  • Came having heard about it

2

  • Family not complete

2

  • Minor SUI

4

  • Declined tape

5

  • Failed TVT-O

3

  • Mixed UDS

1

  • Significant urgency

1

  • Co-morbidities

14

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Details of previous surgery

  • Colposuspension (>15 years)

3

initially successful

  • Vaginal tapes

–TVT (5-8 yrs) (initially successful) 3 – TVT-O recent and failed 1 – TVT-O divided 1 –TVT-O excised 1

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Diagnosis

Stress symptoms/ USI (18) Mixed symptoms / USI (18) Mixed symptoms/ Mixed UDS (19)

n=55

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Outcome by symptoms and diagnosis

2 4 6 8 10 12 14 16 18 20 Mixed /Mixed Mixed / USI SUI / USI DNA No change Slight improvement Big improvement Cured

78% 78% 32% 56% 33% 11%

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Complications

  • One unable to tolerate 3rd injection (80%

cured)

  • One failed to void – catheter with flip flow

valve over night at home – voided on removal – cured

  • One seemed to develop urgency a few

months later

  • Slight haematuria short lived
  • No reported UTIs (prophylactic antibiotics)
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12 months + results

13 replied

(8 cured, 5 big improvement)

4 cured 4 improved 4 cured after second dose 1 failed after RTA

11 did not reply

(1 cured, 6 big improvement, 4 small

improvement)

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Conclusion

  • Bulkamid is an option for all especially

patients who wish to avoid anaesthetics or want another pregnancy or wish to avoid admission and desire short recovery periods

  • It is minimally invasive, relatively quick and

easy

  • Complications appear to be minimal
  • Short term results good for those with USI

even in a population with mixed symptoms

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Why we do it!