Locally Advanced Cervical Cancer S.M.K F/47 referred to CDH with - - PowerPoint PPT Presentation

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Locally Advanced Cervical Cancer S.M.K F/47 referred to CDH with - - PowerPoint PPT Presentation

Jul 13, 2023 302 likes •366 views

Gynecologic Cancer InterGroup Cervix Cancer Research Network Locally Advanced Cervical Cancer S.M.K F/47 referred to CDH with invasive moderately differentiated squamous cell carcinoma of the cervix. Initially diagnosed in July 2017 in

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SLIDE 1

Gynecologic Cancer InterGroup Cervix Cancer Research Network

Locally Advanced Cervical Cancer

  • S.M.K F/47 referred to CDH with invasive moderately

differentiated squamous cell carcinoma of the cervix.

  • Initially diagnosed in July 2017 in Angola
  • Received chemotherapy ?regimen in Angola from July to

December 2017 as radiotherapy unavailable.

  • First seen at CDH 13/06/2018
  • Complained of backache, lower abdominal pain, PVD,

abnormal PVB. RVD NR

  • Rest of systemic review was normal
  • General and systemic physical exam was normal

Cervix Cancer Education Symposium, January 2019, South Africa

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SLIDE 2

Gynecologic Cancer InterGroup Cervix Cancer Research Network

  • Pelvic Exam: 4 X 3cm mass of the cervix
  • Vagina free, Parametria free, Rectal mucosa

free, uteral sacral ligament free

  • Haematology, renal function normal
  • CT scan-mass of cervix 5cm, with endometrial

collection, no visceral or lympnode mets, no hydronephrosis

  • Staged as Cancer of the cervix stage IB2

Cervix Cancer Education Symposium, January 2019, South Africa

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SLIDE 3

Gynecologic Cancer InterGroup Cervix Cancer Research Network

  • The patient received a radical course of concurrent

chemoradiation as follows

  • 46Gy/23 fractions/5weeks to the whole pelvis; APPA

10MV concomitantly with weekly cisplatin 40mg/m2, for 5 cycles.

Cervix Cancer Education Symposium, January 2019, South Africa

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SLIDE 4

Gynecologic Cancer InterGroup Cervix Cancer Research Network At brachy, had responded well to Rx. No parametrial, Vaginal

  • involvement. Cervix smooth 3cm. 7Gy X 4 fractions image guided HDRB

with CT based 3D treatment planning

Cervix Cancer Education Symposium, January 2019, South Africa

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SLIDE 5

Gynecologic Cancer InterGroup Cervix Cancer Research Network

  • On follow up, 3 months later she has NED

FOR DISCUSSION

  • Role of Neoadjuvant chemotherapy in locally advanced

cervical cancer

  • Role of salvage surgery in cases of poor response
  • Contouring in 3D HDRB

Cervix Cancer Education Symposium, January 2019, South Africa