Marine biology and bioinformatics Olga Konovalova Lomonosov Moscow - - PowerPoint PPT Presentation

marine biology and bioinformatics
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Marine biology and bioinformatics Olga Konovalova Lomonosov Moscow - - PowerPoint PPT Presentation

Marine biology and bioinformatics Olga Konovalova Lomonosov Moscow State University Evolutionary genomics lab White Sea biological station Three whales of environmental biology Biodiversity identification ADAPTATION and SPECIES


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Marine biology and bioinformatics

Olga Konovalova Lomonosov Moscow State University Evolutionary genomics lab White Sea biological station

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Three whales of environmental biology

Biodiversity – identification Ecology - adaptation Evolution

ADAPTATION and SPECIES INTERACTION IDENTIFICATION PHYLOGENY

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In terms of molecular genetics and bioinformatics

Gene expression studies Metagenomics Genomics

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At first, biodiversity

Konovalova O. 2012. Mycobiota of brown alga Ascophyllum nodosum (L.) LeJolis in White and Barents seas. PhD thesis. Lomonosov Moscow State University

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Phylogenetic studies

  • Phylogenetics analysis of different group
  • f marine fungi
  • Genomic studies of marine fungus

Acremonium fuci – comparative analysis

  • f mitochondrial genome (almost done)

Konovalova O., Logacheva M. 2015. MITOCHONDRIAL GENOME OF MARINE FUNGUS ACREMONIUM FUCI. Mitochondrial

  • DNA. In press.
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Metagenomics

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  • Metagenomics. White Sea
  • 993 OTUs, 44 identified to genus

level

KonovalovaO., Belevich T., Logacheva M., Milyutina I., Goryunov D. 2015. The first trial of studies of ice mycobiotain White Sea. Materials of 3rd International Mycological Forum, Moscow. Nat. Acad. of Med. Myc. Vol 4.pp. 203-205.

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Problems

  • Biological contamination – sequencing of all

living cells in the sample

  • Genetic contamination – it’s hard to find

universal and specific barcode for eukariots or fungi etc.

  • Data contamination – chimeric sequences
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Metagenomics. Atlantic Ocean, deep-sea sampling

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Thank you!

Maria Logacheva Tatiana Neretina Katya Bubnova

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References to other projects

  • GlafiraD. Kolbasova, Arthur O. Zalevsky, AzamatR. Gafurov, Philipp O. Gusev, Margarita
  • A. Ezhova, Anna A. Zheludkevich, Olga P. Konovalova, KseniaN. Kosobokova, Nikita U.

Kotlov, Natalia O. Lanina, Anna S. Lapashina, Dmitry O. Medvedev, KaterinaS. Nosikova, Ekaterina O. Nuzhdina, GeorgiiA. Bazykin, and Neretina Tatyana. 2015. A new species

  • f Cyanea jellyfish sympatric to c. capillatain the White sea. Polar Biology, pages 1–13.

[ DOI ] DV Abramochkin, OP Konovalova, A. Kamkin, and GF Sitdikova. 2015. Carbon monoxide modulates electrical activity of murine myocardium via cgmp-dependent

  • mechanisms. Journal of Physiology and Biochemistry, 71(1):107–119. [ DOI ]