Recap Alife 2008 Walter de Back Collegium Budapest Institute for - PowerPoint PPT Presentation

Recap Alife 2008 Walter de Back Collegium Budapest Institute for Advanced Study

Prebiology: Error threshold Eigen, 1971

Hypercycles on a surface Boerlijst, Hogeweg 1991

Metabolic model Czaran, Szathmary 2000

Hypercycles vs. Metabolic model 1 / n   = ∏ n ( )   M x x i   = i i

Genotype - Phenotype RNA folding

Neutral networks

RNA evolution

RNA evolution

Cellular Potts model aka Glazier-Graner-Hogeweg model ● Two-scale cellular automata model ● Cell movement / Tissue development by Differential Adhesion – Free energy bond J ij where i and j are the types of the cells – Sites changes state as to minimize free energy

Gene regulation (Boolean) network Nodes have state 0 or 1 NK-network: Nodes have logical rules (gates): ● N nodes e.g. ● K connections

Gene regulation (Boolean) network Sample network Activation pattern (here: periodic)

Evolution of reproductive restraint Spatial self-structuring => Multi-level selection => Natural selection for less fit individuals