Veterinary Vaccinology Network Early Career Vaccinologists Journal - PowerPoint PPT Presentation

Veterinary Vaccinology Network Early Career Vaccinologists Journal Club 08-05-15 Andrew Broadbent

Codon bias

Codon pair bias

Influenza

influenza

Discussion • Pros – No phenotypic reversion to virulence – DIVA vaccine • Cons – Shedding of mutant viruses and reassortment of mutant viruses with wt viruses might have unpredictable outcomes – Regulatory concerns for influenza