Veterinary Vaccinology Network Early Career Vaccinologists Journal - - PowerPoint PPT Presentation

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Veterinary Vaccinology Network Early Career Vaccinologists Journal - - PowerPoint PPT Presentation

Jul 31, 2023 32 likes •204 views

Veterinary Vaccinology Network Early Career Vaccinologists Journal Club 08-05-15 Andrew Broadbent Codon bias Codon pair bias Influenza influenza Discussion Pros No phenotypic reversion to virulence DIVA vaccine Cons

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Veterinary Vaccinology Network Early Career Vaccinologists Journal Club 08-05-15

Andrew Broadbent

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Codon bias

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Codon pair bias

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Influenza

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influenza

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Discussion

  • Pros

– No phenotypic reversion to virulence – DIVA vaccine

  • Cons

– Shedding of mutant viruses and reassortment of mutant viruses with wt viruses might have unpredictable outcomes – Regulatory concerns for influenza