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Medical Radiation Physics Department of Physics Stockholm - - PowerPoint PPT Presentation
Medical Radiation Physics Department of Physics Stockholm - - PowerPoint PPT Presentation
Medical Radiation Physics Department of Physics Stockholm University Medical Radiation Physics - MSF Natural Sciences Faculty Medical Radiation Physics Research Group Medical Radiation Physics Department of Oncology-Pathology Division
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MSF
Iuliana Toma-Dasu Niels Bassler Irena Gudowska Marta Lazzeroni Emely Kjellsson Lindblom Postdoc Helena Sandström Researcher/Collaborator Ana Ureba PhD students Tomas Palmqvist Fredrik Kalholm Filippo Schiavo Wille Häger MSc students On average 10 students per year
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Medical Radiation Physics - MSF
- MSc program in Medical Radiation Physics
/ Professional education
- About 8 MSc students/year on average
Education
Radiotherapy Radioprotection Radiobiology Dosimetry Imaging
Research
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MSF – Medical Radiation Physics
- Medical Radiation Physics is a vast and complex translational research topic that deals with
radiation physics applied to medicine and biology for medical radiation imaging and radiation therapy - possible collaboration across Fysikum - or beyond Fysikum Radiation Sources Detectors Dosimetry Radiation Biology Radiation Interaction Diagnostic Radiology Radiation Therapy Radiation Protection Nuclear Medicine
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MSF - Possible Supervisors at Fysikum
- Potential BSc supervisors at Fysikum, e.g.:
○ Bo Sundborg ○ Michael Odelius ○ Mark Stockett ○ Tony Hansson ○ Henrik Öström ○ Samuel Silverstein ○ Fredrik Hellberg ○ Alfredo Ferella ○ …
BSc projects topics may involve:
- any kinds of radiation interaction
- aspects of dosimetry or quantifying radiation fields
- accelerator physics
- interdisciplinary physics topics involving
chemistry and/or biology
- detectors
- image analysis
- ...
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Examples of BSc projects
Title Conducted at Supervisor(s) MSF Supervisor Collision induced fragmentation of thymine clusters Fysikum Mark Stockett Design and construction of a compact radiation dosimeter for calibration and mapping of radiation fields in confined irradiation chambers Fysikum/RB Samuel Silverstein Andrzej Wojcik Spatial frequency-based objective function for optimization of dose heterogeneity in proton grid therapy UU Anders Ahnesjö Simulation of stray radiation in the XFEL undulator using FLUKA Fysikum/MSF Fredrik Hellberg Niels Bassler Characterization of Gafchromic films for applications Fysikum Fredrik Hellberg Investigating the influence of water in lysozyme structure and dynamics using FT-IR and XRD Fysikum Foivos Perakis Dosimetry at the European XFEL using Gafchronic films in beginning of undulator SASE1 Fysikum Fredrik Hellberg Radiation damage to isolated DNA builiding blocks Fysikum Mark Stockett Dosimetric Characterisation of an Alcyon II Medical 60Co Irradiation Unit MSF Niels Bassler Modelling the cell survival using the RCR model MSF Iuliana Toma-Dasu Emely Kjellsson Lindblom
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Research at MSF
- Radiotherapy
- the use of ionising radiation in the
management of malign and benign diseases
- Radioprotection
- assessing and minimising the risk of stochastic
detrimental effects of radiation such as induction of cancer after medical radiation exposures
- improving preparedness and competence in
Sweden to cope with nuclear emergencies
- https://www.fysik.su.se/english/medical-radiation-physics/research
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Treatment outcome modelling
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Customised RT based on functional imaging
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MSF – Proton Therapy
➢ Proton treatment planning comparison to photon therapy ➢ Proton treatment evaluation and
- ptimisation
➢ Radiation protection aspects related to the risk of secondary cancer following proton therapy
- Collaboration with Skandion Clinic (Uppsala):
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Radiation Interaction in Media
CRT Development of fast and precise calculation tools for innovative treatment planning Development of radiation detector models for ion radiation, for better dosimetry
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Radiation Protection
From anthropomorphic phantoms to patients
Secondary doses to healthy tissues from radiotherapy and modern imaging techniques => Risk of secondary cancer CRT IMRT
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Radiation Protection
Dosimetric approaches for protection of people in large-scale nuclear emergencies CRT IMRT
Area where the effective dose exceeds 20 µSv in a time interval of 120 minutes after the event of an explosion involving Ir-192 sources.
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MSF - Industry and Innovation
- Treatment
planning based
- n
tumour hypoxia
- Adaptive RT based on advanced
imaging techniques
- Evaluation
and selection
- f
treatment plans using functional and radiobiological information
- Variability
in target and OARs delineation for SRS
- Robust treatment planning for SRS
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Examples of MSc projects
Title Conducted at Supervisor(s) MSF Supervisor A deepened experimental evaluation of radiation detectors to measure depth dose curves in water for 106Ru ophthalmic plaques by use of a new precision setup equipment NKS Åsa Carlsson Tedgren Clinical evaluation of radioiodine treatments for hyperthyroidism NKS Joachim Nilsson Oscar Ardenfors Jan Calissendorff Image quality and optimisation in conventional diagnostic radiology Huddinge Axel Carlbring Tiina Voima Hellebring Image-derived input functions for non-invasive measurement of cerebral blood flow using 15O-water and PET Akademiska Uppsala Mark Lubberink Investigating the potential of CBCT for setup and treatment verification in proton therapy for prostate cancer Skandion/ Akademiska/MSF Alexandru Dasu Ulf Isacsson Silvia Johansson Ana Ureba Experimental investigation of the reference dosimetry correction factors for Leksell Gamma Knife Perfexion beams published in TRS-483 NKS Hamza Benmakhlouf Vaiva Kaveckyte Risk of second cancer from proton therapy of breast cancer - impact of physiological and radiobiological uncertainties Skandion/MSF Alexandru Dasu Iuliana Toma-Dasu Jakob Öden Oscar Ardenfors Assessment of image quality in x-ray fluoroscopy based on Model Observers as an objective measure for quality control and image
- ptimization
Linköping Mikael Sandborg Erik Tesselaar Clinical optimization of a regularized reconstruction algorithm in PET NKS Alejandro Sanchez Crespo Evaluation of a method for simplified image quality control of dental CBCT units Danderyd Karin Näsström Jerker Edén Strindberg Development of a grid-specific proton optimizer MSF Ana Ureba Thomas Henry
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